Levo-Alpha Acetyl Methadol (LAAM).
Its advantages and drawbacks

by
Finn P, Wilcock K
Abt Associates Inc.,
Cambridge, MA 02138-1168, USA
J Subst Abuse Treat 1997 Nov-Dec; 14(6):559-64


ABSTRACT

Levo-Alpha Acetyl Methadol, or LAAM, is a medication therapy for individuals addicted to opiates that provides an alternative to methadone. Because it is administered only three times a week and, therefore, requires fewer clinic trips, patient acceptance can be higher than with methadone. While blocking the effects of other opiates and preventing withdrawal, LAAM does not produce a subjective high. However, because most patients are not familiar with LAAM, they may be initially more anxious and need more counseling and support when receiving the medication than they would with the more familiar methadone medication. On balance, LAAM enables clinic administrators and counselors to offer an alternative medication to methadone that some clients prefer once they become adjusted to it because of LAAM's even, stable effect. Through hypothetical but true-to-life case studies of LAAM use, it is possible to gain a clearer understanding of the advantages and drawbacks of using LAAM.
Pain
Heroin
Arousal
Fentanyl
Tramadol
Tolerance
Nociceptin
Lofexidine
Poppy tea
Methadone
Remifentanil
Endomorphins
Buprenorphine
LAAM : structure
LAAM v methadone
LAAM : pharmacodynamics


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